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Carnosine, small but mighty-prospect of use as functional ingredient for functional food formulation

We also found a positive effect of AOX supplementation on total sperm motility after the exclusion of studies carried out in patients with varicocele or treated with varicocele repair and AOX or placebo/no treatment [27, 28, 29, 30, 31, 32, 50, 55], including a total of 4,291 infertile men (MD 7.29% [95% CI: 2.75, 11.83]

Relevant to the mechanism of PKC downregulation by antidepressants and valproate (see below), acute lithium use mimics the effect of phorbol esters with resultant activation of PKC (energizing immediate early genes such as c-fos), while chronic lithium use attenuates the phorbol ester action on PKC, down-regulating the enzyme (Manji and Lenox, 1994)

Billah M, Rohman MM, Hossain N, Uddin MS (2017) Exogenous ascorbic acid improved tolerance in maize ( Zea mays L.) by increasing antioxidant activity under salinity stress