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These medications alter one of the fundamental processes of the human body, weight regulation, by: reducing appetite and consequently energy intake, increasing energy expenditure, redirecting nutrients from adipose to lean tissue, or interfering with the absorption of calories

In chronic blood loss , the sustained but slower hemorrhage gradually depletes iron stores (ferritin serum iron bone marrow iron TIBC elevation hemoglobin fall), producing the classic microcytic hypochromic pattern of iron deficiency anemia (D50.0)

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