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Some neonatal studies show no depletion at therapeutic doses, suggesting babies may metabolize it differently

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The exact how is unclear , but it might change how thyroid hormones work

The liver uses this same system in bile acid synthesis and the hydroxylation of cholecalciferol to 25-hydroxycholecalciferol (vitamin D3;), and the kidney uses it to hydroxylate vitamin D3 to its biologically active 1,25-dihydroxylated form