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Acknowledgements This research was funded by the Guangdong Provincial Department of Education as a scientific research project (2024KQNCX133), Zhanjiang Marine Youth Talent Project (2024R3004), the National Natural Science Foundation of China (82103834) and the Innovative Research Group of Functional Food Development and Quality Analysis (ZY24PYTD05)

For example, YY1-K183la promotes the polyubiquitination of p53 at K291/292 by facilitating the transcription of FBXO33 in GBC

The most common IV insulin vitamins are Vitamin B-Complex, and Vitamin C

For example, the increased dosage of CBS and GCS in our simulation of Down syndrome causes the intracellular concentration of cysteine to decline while the blood concentration increases