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Its unique interaction with neuroendocrine pathways has led to ongoing research into how sleep-related peptides may influence overall metabolic and physiological balance

The differing toxicities of ionizable organic compounds at different pH values can be attributed to the distinct permeabilities of the existing species (i.e., neutral and ionized forms) because neutral species can permeate biomembranes and become trapped in cells faster than the corresponding charged species, resulting in distinct differences in the internal concentrations