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Children presenting neurological signs or symptoms, those unable to take oral medication, individuals with known malabsorption syndromes, infants under 6 months old, and patients using medications that may interfere with vitamin B12 absorption are typically treated with a parenteral protocol (1)

But interesting biology and plausible mechanisms are where drug development begins, not ends

Age-related thinning that isn't driven specifically by DHT sensitivity also involves DPC decline: reduced scalp circulation delivers fewer nutrients to the papilla, oxidative stress accumulates over time, and cell renewal slows

Potential cognitive benefits: Studies suggest it may have positive effects on cognitive function, including memory and learning