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Description

These data provide strong in vivo evidence that concomitant reduction of cystine uptake, transsulfuration and GPX4 activity can be utilized as a new therapeutic strategy for high-risk, MYCN -amplified neuroblastomas

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Inactivation of SOD1 causes hepatocellular carcinoma

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Recently introduced, the use of blood succinylacetone (SA) as the NBS marker is predicted to identify all infants affected with HT-1

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This information suggests that fine regulation of the redox system is key to cellular proteostasis

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