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01, 2026 Neurogenetic Disorders May

It can inhibit angiogenesis in rheumatoid arthritis by targeting the interleukin (IL)-6/Janus kinase 2 (JAK2)/signal transducer and activator of transcription 3 (STAT3)/vascular endothelial growth factor (VEGF) signaling pathway [13] and also has the potential to treat primary biliary cholangitis [14] and multiple sclerosis [15]

We have precisely described the roles of oxidative stress and examples of PTMs (e.g., oxidation, S -nitrosylation, JNK-mediated phosphorylation, nitration, acetylation, and adduct formation) of mitochondrial proteins and transcription factors in promoting fat synthesis, mitochondrial dysfunction and apoptosis of hepatocytes, leading to individual liver diseases caused by different etiological agents