glutathione connection to nad Redox potentials of NAD(P), glutathione, and ascorbate couples. Adapted Interplay between NADH oxidation by

Mijangos-TrejoANuo-LambarriNBarbero-BecerraVUribe-EsquivelMVidal-CevallosPChvez-TapiaN

demonstrated that activation of PKD leads to its autophosphorylation and subsequently promotes ferroptosis by activating the p53-SLC7A11 axis

In summary, ferroptosis contributes to retinal ischemiareperfusion injury, and blocking ferroptosis reduces RGC loss and inflammation

James et al., 2015), that catalyses (phospho)lipid hydroperoxide propagation, using salicylaldehyde isonicotinoyl hydrazone (SIH, 250 M), a lipophilic acylhydrazone that scavenges intracellular iron and mobilizes it for extracellular clearance (Kalinowski and Richardson, 2005)