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9.5 Antidiarrheal activity Recently, Qu et al found that ISA could suppress the ATP and E act -stimulated short-circuit current in HT-29 cells having TMEM16A, a Ca 2+ -activated Cl channel (CaCC), with IC 50 of 9.2 M and 11.8 M, respectively (Qu et al., 2023)

Use as many equivalents of the cofactor, acid, and base as you need

It is mediated by kinesin-1, which binds to mitochondria via anchoring proteins including the microtubule-associated motors dynein-dynactin, the Ca 2+ -dependent mitochondrial Rho GTPase 1 (Miro1), and the trafficking kinesin proteins 1 and 2 [45]