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LEfSe analysis provided a secondary measure to establish differences between treatment groups in addition to the one-way ANOVA/KruskalWallis tests performed on each genus/phylum

Do not administer pemetrexed for injection when the absolute neutrophil count is less than 1500 cells/mm3 and platelets are less than 100,000 cells/mm3

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Rapid injection increases discomfort and may cause the medication to leak back out of the injection site