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Clinical relevance of the ACTL6A-GCLC-GSH metabolism axis in ferroptosis of GC cells Next, we sought to determine the clinical relevance of ACTL6A in regulating GCLC and inhibiting ferroptosis in a patient-derived xenograft (PDX) model

For example, Khan et al

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On the one hand, these observations might be explained by the fact that an estrogen drop is required for the onset of ovulation 88 , and several flavoproteins (proteins using FMN and FAD as coenzyme) assist estrogen degradation by cytochrome P450 51,89 as they balance electrons from these reactions