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Overall, cannabinoids might exert protective effects on carcinogenesis directly, through activation of cannabinoid receptors, or indirectly, through elevation of endocannabinoid levels via inhibition of metabolizing enzymes (particularly FAAH)

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According to another study, glutaminolysis increases the level of -KG production, resulting in GTP loading of RagB and lysosomal translocation of the mTORC1 complex in human cancer cell lines 160

SUD has three subdomains: SUD-N (Mac2), SUD-M (Mac3) and SUD-C (DPUP)