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While HNF4 possesses several serine residues within its analogous hinge region, its paralog, HNF4, shares more sequence similarity to NHR-49 and exhibits a higher degree of conservation at the respective serine residue and its surrounding motif (Supplementary Fig

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Other risks include thermal burns from heated solutions, strictures (intestinal narrowing), bowel perforation, rectal burns, nausea, vomiting, cramping, bloating, dehydration and infections