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Kremennaya MA, Soldatov MA, Podkovyrina YS, Dadasheva IA, Soldatov AV

This is common with a knee joint injection

They can cause side effects, including: [5] Mild pain or burning at the injection site Temporary swelling or redness Bruising under the skin An erection lasting more than 4 hours is a medical emergency and requires urgent care to avoid permanent damage Prolonged erection (priapism): This can occur if injections are used excessively or with poor technique Scar tissue or penile curvature: These symptoms may indicate an emergency

Some patients begin with one medication and add the second later if they hit a plateau, need stronger appetite control, or would benefit from a different mechanism