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Here we review the structure, ligand, signaling pathways, and expression of TLRs

IL-22 primarily acts on keratinocytes by promoting hyperproliferation and de-differentiation and by inducing the release of chemokines (CXCL1, CXCL2, CXCL8, CCL20), and AMPs (HBD-2, HBD-3, S100 proteins) [30, 31]