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Nicotinamide N-methyltransferase: metabolic regulator and emerging therapeutic target (2024 review)

[5] Liu T, Liu Y, Zhao X, Zhang L, Wang W, Bai D, Liao Y, Wang Z, Wang M, Zhang J

This actin-buffering capacity is critical for dynamic cellular processes including: Cell migration: Rapid actin polymerization at the leading edge Morphological changes: Cytoskeletal reorganization Intracellular transport: Actin filament dynamics The peptide contains a conserved LKKTETQ actin-binding motif that is essential for its interaction with G-actin

Its found in high concentrations in animal products, especially red meat, and is essential for red blood cell formation, DNA synthesis, brain development, and nervous system function