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It was found that the mucoadhesive properties of CS can provide higher drug bioavailability by increasing permeation across ocular barriers

LINK Tubbs RS, Loukas M, Callahan JD, Cohen-Gadol AA: A novel approach to the upper anterior thoracic spine: a cadaveric feasibility study

Since UPR is involved in NF-B activation and ROS production, which are related to the activation of the NLRP3 inflammasome, these controversial results call for further insight into UPR pathways as inflammasome mediators (Figure 3)

The samples were sonicated for 2 min (pulse on: 10 s, pulse off: 5 s) with an amplitude of 25% (Sonic Dismembrator Model 120, Thermo Fisher Scientific, Waltham, MA, USA)