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Finally, even when CHE is identified as conferring a high risk for traffic accidents and therapeutic intervention is initiated, determining how best to address patients actual driving practices remains clinically and ethically complex, particularly in societies with limited alternative transportation options

[Historical review of gout and hyperuricemia investigations]

Aunque el enfoque principal fue la optimizacin de la utilizacin de grasas como fuente de energa, se observ una ligera tendencia a la mejora en la composicin corporal (aumento de masa magra y reduccin de masa grasa)