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Brain uptake of [C]-verapamil, a substrate of P-gp that is physiologically extruded quickly, was measured by positron emission tomography (PET)

S.HildebrandtL.PrumeJ.LoderM

Nat Genet 37(11):12341241

Also, crosstalk with other signaling pathways such as transforming growth factor-beta (TGF-) has led to carcinogenesis and resistance to targeted therapies in human lung, pancreatic, and breast tumor xenografts [17]