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Lapatinib is commonly used in the treatment of HER2 positive breast cancer but is prone to recurrence due to drug resistance (Yuan et al., 2023

However, a large bilirubin pool requiring elimination, such as in hemolytic disease of the newborn, may overwhelm the excretory capacity with efflux of backed-up conjugated bilirubin into the serum

Indeed, gp96 can be re-presented by antigen presenting cells via cell surface receptor CD91, whereby the chaperone and its bound peptide are endocytosed

For 2024, tapentadol and dihydrocodeine were added to monitor patterns of use in-competition, and semaglutide (GLP-1 analog) was added to examine prevalence of use in sport

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