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Description

Measurement of liver enzymes such as ALT and AST are not very useful in this context, since they represent acute cell death and peak levels of ALT and AST are not predictive of clinical outcome [157,162]

Spectroscopic studies of anthracyclines: Structural characterization and in vitro tracking

Aqueous solubility facilitates transport within the blood and excretion via the kidney, while a lipophilic chelator may exhibit greater penetration of cellular membranes (including those within the central nervous system) to chelate intracellular elements