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To clarify how the TSS pathway is activated, we first evaluated the effects of hypoxia in the presence of supraphysiological concentrations of cystine

S2CID 6263928

While MSCs may be an attractive alternative source to ESCs in cell-based therapies, difficulty in continued proliferation in vitro , off-target differentiation into other cell types, fibrotic changes, and cellular senescence are issues that have yet to be fully addressed