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Intriguingly, this study showed that Syn 1103 with a fully exposed hydrophobic core exhibited much stronger binding affinity for BSA compared to Syn S129E and also inhibited Syn 1103 aggregation

These neurodegenerative processes occur partly independently of intraocular pressure, but changes in the trabecular meshwork can also impair the regulation of intraocular pressure (IOP)

According to the American Academy of Pediatrics clinical practice guideline [4], children having acute upper respiratory tract infection with (1) persistent illness lasting for more than ten days without improvement, (2) worsening course after initial improvement or (3) severe onset for at least three consecutive days could be diagnosed of acute bacterial sinusitis

DeVries AC, Joh HD, Bernard O, Hattori K, Hurn PD, Traystman RJ et al