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PMID: 41833924 Cell Death Dis RHBDL2 drives lipid metabolic reprogramming in osteosarcoma via USP3-mediated deubiquitination of PPT1

The results imply that application of exogenous GABA can feed back to the TCA cycle to promote the carbon and nitrogen cycle

Preprint at bioRxiv (2025)

A multicenter phase II study of the efficacy and safety of quisinostat (an HDAC inhibitor) in combination with paclitaxel and carboplatin chemotherapy (CT) in patients (pts) with recurrent platinum resistant high grade serous epithelial ovarian, primarily peritoneal or fallopian tube carcinoma cancer (OC)