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( f ) Quantification of H2AX foci in cells transduced with shRNA targeting IDH1 alone or combined with overexpression of wildtype IDH1 (wtIDH1 OE) (n = 3 technical replicates from 3 independent experiments in each cell line)

Consideration: While it may aid in weight loss for some people, it should be considered a supplement to, not a replacement for, a thorough diet and exercise regimen developed with professional nutritional counseling

Ramaekers et al., 2007

Interestingly, the researchers noted that combining the two forms resulted in less overall improvement than using them individually, suggesting a potential competition for intestinal absorption or cellular transport mechanisms