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Increased stress susceptibility and impaired differentiation of astrocytes and neurons was found in co-cultures and in neural organoids generated from AxD patient-derived induced pluripotent stem cells with AxD-causing GFAP R239C mutation 334

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391 Human UC-MSCs were induced to transform into dopaminergic neurons in vitro, and transplantation of these cells into the striatum of rats with PD partially corrected injury-induced rotation