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But more research needs to be done

Primary antioxidants are made by the body, thus internally provided

doi: 10.1007/s10725-018-0403-7 9 ChengZ

Since previous studies reported aberrant mitochondrial morphology in AS [10], and we previously observed that Ube3a -null MEFs exhibit altered mitochondria-associated pathways [29, 30], we posited that the AS mitochondrial abnormalities culminate in a reduced capacity of the mtGSH to control mROS accumulation