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HMs are distinguished by having a higher atomic weight or density of over 5 g/cm 3 and can be classified into essential HMs such as zinc (Zn), iron (Fe), copper (Cu), and manganese (Mn), and non-essential HMs such as arsenic (As), cadmium (Cd), chromium (Cr), lead (Pb), and nickel (Ni) [6, 7]

While more severe forms are not all that common, some research estimates that MCAS could affect up to 17% of the population on a spectrum from very mild to debilitating symptoms.[ref] Others include very mild symptoms such as allergic rhinitis in the mast cell activation spectrum, which includes up to 30% of the population.[ref]

General Aggregation-Induced Emission Probes for Amyloid Inhibitors with Dual Inhibition Capacity against Amyloid -Protein and -Synuclein

Lee CS, Hwang G, Nam YW, et al