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and magnesium, citrate, and potassium loss (Heseltine 1988

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Although vitamin B12 deficiencies are relatively rare in people who consume enough animal products, vegans, vegetarians and people with certain digestive problems (such as stomach problems that affect B12 absorption) may develop a deficiency

Additionally, the constrained confirmational changes during the simulation process are confirmed by the histogram of RMSD of various ligands (Fig