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3.1.1 Impact of ROS on cellular function and atherosclerosis Elevated ROS can induce endothelial cell dysfunction or death, disrupting the vascular barrier and leading to vasoconstrictive and vasodilatory dysfunction, vascular smooth muscle cell proliferation and migration, inflammatory responses, and thrombosisprocesses intimately associated with various cardiovascular disorders, including atherosclerosis, hypertension, and CHD (31)

[DOI] [PubMed] [Google Scholar] 52.Xu L., Zheng R., Xie P., Guo Q., Ji H., Li T

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This overwhelms the iron homoeostasis and iron clearance system, finally leading to an iron-overloaded environment in peritoneal fluid and ectopic lesions of endometriosis [88]