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This phase will incorporate standardized sample processing and will include the evaluation of the nine model genes using Immunohistochemistry (IHC) scoring at the protein level, which is critical for direct clinical application

Pharmacological Inhibition of the GST Family or Activation of Ferroptosis Attenuates the Development of EMs Currently, highly selective pharmacological inhibitors specifically targeting MGST3 are not available

Long-term HFD consumption reduced hepatic expression of glutaredoxins The de-glutathionylation of protein-mixed disulfides is primarily catalyzed by glutaredoxins (Grxs) 31