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In a phase 1 trial treating patients with relapsed pleural mesothelioma and malignant pleural effusion (NCT05278975), weekly local intrapleural treatment with the TS formulated drug product RSO-021 at 90 mg is well tolerated leading to disease control in 67% of patients at 12 weeks and is associated with tumor reductions

Mller JC, Krttgen A, Heymach JV , Ghori N, Shooter EM

Aghfack-Nguemezi, J., Passannet, A

The utilization of ECMO in adults with severe ARDS was shown a significant reduction in 60-day mortality when compared to conventional mechanical ventilation (253)