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SAMe also serves as a precursor molecule to the aminopropylation pathway, which leads to the synthesis of polyamines, and the transulfuration pathway, which leads to the synthesis of glutathione

A study in rats showed that Nigella sativa increased glutamate and GABA in different areas of the brain.[ref] Im not exactly sure how the study would apply to humans, but I included it to show that Nigella sativa could be affecting amino acid neurotransmitter levels, including glutamate

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Monthly plans work well for patients who want to test a formulation before committing to a longer supply or who prefer smaller, more frequent payments