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[DOI] [PMC free article] [PubMed] [Google Scholar] 121.Burgaz S., Garca C., Gmez-Caas M., Muoz E., Fernndez-Ruiz J

As glutamine levels drop in the TME, T cells and NK cells experience functional impairment, including reduced production of IFN-, thereby diminishing the cytotoxic immune response against the tumor [63]