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In view of the pivotal role played by GSH in redox system and the relationship between oxidative stress and autophagy 68 , it is conceivable that GSH depletion-induced oxidative stress and lipid peroxidation may be a key point linking ferroptosis and autophagy in RPE cells

Gong et al., 2019)

Oxidative stress is the consequence of the imbalance between the bodys immune system mechanisms and reactive oxygen species (ROS), resulting in cellular damage (85)