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2005;128:617S

Renal cortical and medullary tissues were collected and stored in the RNA later solution (Thermo Fisher Scientific Inc.) until use

All participants followed a calorie-restricted diet (~300 kcal/day deficit)

In addition to serving as a substrate for glutathione related enzymes, GSH acts as a free radical scavenger, a generator of a -tocopherol and plays an important role in the maintenance of protein sulfhydryl groups (42)