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10.3389/fimmu.2025.1722777 27 ChengD.ShamiG

Among the general neurological symptoms assessed in humans, several studies reported on fatigue, sleep disturbances, and/or dizziness

The main pathological hallmark of PD is the degeneration of dopaminergic neurons in the substantia nigra, resulting in dopamine deficiency and subsequent motor symptoms like bradykinesia, rigidity, and tremors [2]