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Changes in MMA, C3, tHcy and methionine levels and mental development were monitored during treatment

Recently, it was observed that VPA administration in Huh7 cells caused cell damage through the process of endoplasmic reticulum stresscaused due to the oxidation of glutathione (GSH) to glutathione disulfide (GSSG) as a consequence of GSH involvement in oxidative protein folding 15 and lipid peroxidation

Given the relevance of TGs content to the development of MASLD and MASH, these lipids may be used as biomarkers for the non-invasive diagnosis of MASLD and MASH (10)