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It has been shown to improve protein, enzyme, and bilirubin levels, as well as to reduce markers of cellular damage in the liver

Lam et al., 2012

At the heart of these processes are the NF-B and MAPK signaling pathways, which control the transcription of pro-inflammatory mediators including COX-2, CRP, LOX-2 and cytokines IL-1, IL-6, IL-8 and TNF- (9799)

Suppression of Cx43 hemichannels via intrathecal injection of blockers such as Gap26, Gap27 or Peptide 5 reduces the production of chemokines CXCL1 and CXCL12, as well as cytokines IL-1 and IL-6, in various neuropathic pain models, including nerve injury, chemotherapy-induced and bone cancer models 496,498,504,505