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Answers to these questions will further illuminate the ferroptosis pathway and open attractive cues to systematically explore the benefit of ferroptosis therapeutic interventions in curing liver diseases

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The mitochondrial genome is especially susceptible to oxidative damage due to proximity to ROS generated during respiration

The total Fluoro-Jade C+ cell counts for each quantified coronal section were then averaged into a single data point representing neurodegeneration in each animal (number of fluorescent cells per field area)