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Food Chemistry,301, 125286

Nitric Oxide ( ) is a reactive free radical, with a half-life in vivo (about 10 seconds) that is slightly longer than the more reactive free radicals, superoxide anion ( 0 - ) and hydroxyl ( )

Subcutaneous injection near the abdomen targets gut-related effects more directly, while oral peptide capsules offer an alternative delivery method that directly contacts the GI mucosa