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Clin Immunol (Orlando, Fla) 215:108448108448 Zenewicz LA (2018) IL-22: There is a gap in our knowledge

Khoshandam A, Imenshahidi M, Hosseinzadeh H (2022) Pharmacokinetic of berberine, the main constituent of Berberis vulgaris L.: A comprehensive review

The limited understanding of basic underlying mechanisms and their complex interplay involved in the pathophysiology has led to chronic pain remaining a significant unmet medical need