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Overlap between Included Systematic Reviews Table 11Primary Study Overlap between Included Systematic Reviews Appendix 6

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However, several conditions can decrease the efficiency of carnitine reabsorption and, correspondingly, increase carnitine excretion

SREBP transcription factors, particularly SREBP-2, coordinate mevalonate pathway flux to generate prenylation substrates farnesyl pyrophosphate (FPP) and geranylgeranyl pyrophosphate (GGPP) through regulated intramembrane proteolysis (198, 201, 202)