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3.1.4 Roles of epigenetically mediated ferroptosis in I/R AKI Ubiquitination regulates signaling via mediating protein turnover, with deubiquitination reversing this process by detaching ubiquitin from substrates

Male SpragueDawley (SD) rats weighing 200 20 g were obtained from the Animal Experiment Center of the Fourth Military Medical University (Xian, China) and housed in a specific pathogen-free animal facility

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When you take acetaminophen, most of it is metabolized safely, but a small portion is converted into NAPQI (N-acetyl-p-benzoquinone imine) , a toxic byproduct