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Chen and Gong, 2022a)

This metabolic insult is compounded by ROS-induced endoplasmic reticulum stress, marked by the upregulation of UPR components like CHOP and GRP78, which further promotes hepatocyte apoptosis and inflammatory activation (Zhang et al., 2022)

Soluble proteins contain essential amino acids and bioactive peptides that contribute to various health benefits, including antibacterial, antioxidant, and anti-inflammatory properties ( 3.3 Differences in functional components of frost mulberry leaves among different varieties The results of the flavonoid, polyphenol, anthocyanin, resveratrol, chlorogenic acid, and ascorbic acid content measurements in frost leaves from different mulberry varieties are presented in Table 4

The following indices were evaluated ( n = 8 mice per group)