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"Reduction in glutathione peroxidase 4 increases life span through increased sensitivity to apoptosis"

One way in which Htt aggregates could cause toxicity is through depleting ubiquitin, a protein that binds to misfolded proteins to promote their clearance through the ubiquitin-proteasome system ( Notably, the N-terminal 17-residue domain stretch of huntingtin folds into an amphipathic -helix in the presence of membranes (Pandey et al., 2018)

These results demonstrate that Mlkl / MuSCs display lower proliferation ability

Therefore, IgA secretory B cells play an extremely important role in the regulation of intestinal flora and the intestinal mucosa defense