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Those S-100 + , GDNF + , or BDNF + cells but not co-expressing human nuclei might be host Schwann cells with an injury-induced repair phenotype characterized by enhanced proliferative, migratory, and invasive capabilities [5, 56], which might have migrated through the damaged epineural barrier to the perineural areas

4d) suggests significant changes in the expression of genes related to a range of metabolic signalling networks, including lipid, protein, nucleotide, carbon and reactive oxygen species metabolism

[8] One such potential pathway involves the activation of phospholipase C (PLC), which researchers suggest may lead to the release of inositol triphosphate (IP3) and diacylglycerol (DAG)