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In agreement, several studies have reported a downregulation of endocytosis in proximal tubule cells exposed to cadmium [106] and a reduced endocytosis/phagocytosis capacity in dendritic cells and macrophages subjected to arsenic stress [107][108][109]

Imboden C, Gerber M, Beck J, Eckert A, Phse U, Holsboer-Trachsler E, Hatzinger M (2019) Effects of aerobic exercise as add-on treatment for inpatients with moderate to severe depression on depression severity, sleep, cognition, psychological well-being, and biomarkers: study protocol, description of study population, and manipulation check

It is best to consult a healthcare professional before combining supplements to avoid potential interactions

You can support a healthy microbiome by eating lots of fibre to feed the gut bacteria, also known as prebiotics