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It was suggested that certain combinations, particularly a GHK-Cu to LMW HA ratio of 1:9, significantly increased the synthesis of collagen 4 compared to when either compound was examined alone

Arjinpathana et al., Journal of Dermatological Treatment: In a randomized, double-blind, placebo-controlled study, researchers found that oral glutathione significantly reduced melanin indices across various body sites compared to the placebo group

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